8 results
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Rapid eye movements that repositions the eyes to a new location.
Reference:
ScienceDirect Topics. Saccades and fixation [Internet]. [cited 2025 Nov]. Available from: https://www.sciencedirect.com/topics/engineering/saccades-and-fixation
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The overall assessment of a drug’s adverse effects, tolerability, and risk characteristics.
Reference:
EU Clinical Trials Register. Glossary [Internet]. [cited 2025 Nov]. Available from: https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
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The number of subjects involved in a study. A larger sample size provides stronger evidence, as it is associated with greater statistical power.
Reference:
ScienceDirect Topics. Sample size [Internet]. [cited 2025 Nov]. Available from: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/sample-size
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An adverse event that results in death, is life-threatening, requires or prolongs hospitalization, causes significant disability, or involves a congenital anomaly or other medically important condition.
Reference:
National Center for Biotechnology Information (NCBI). MedGen: Serious adverse event [Internet]. [cited 2025 Nov]. Available from: https://www.ncbi.nlm.nih.gov/medgen/276798
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A natural process in cells that edits genes by cutting out unnecessary parts and joining the useful sections together to make a complete instruction for building a protein.
Reference:
ScienceDirect Topics. DNA splicing [Internet]. [cited 2025 Nov]. Available from: https://www.sciencedirect.com/topics/neuroscience/dna-splicing
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Care given to patients that includes symptomatic treatment but also focuses on improving overall quality of life. In PSP, supportive care can involve physical, occupational and speech therapy and nutritional and psychological support to help patients manage the disease and maintain their independence for as long as possible.
Reference:
Rowe JB, Holland N, Rittman T. Progressive supranuclear palsy: diagnosis and management. Pract Neurol. 2021;21(5):376-383. doi:10.1136/practneurol-2020-002794
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Impaired voluntary eye movements, especially vertical gaze, more than in the horizontal plane, affecting both up- and downgaze.
Reference:
Höglinger GU, Respondek G, Stamelou M, et al. Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Mov Disord. 2017;32(6):853-864. doi:10.1002/mds.26987
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Interventions aimed at alleviating symptoms of a disease rather than addressing the underlying cause.
Reference:
ScienceDirect Topics. Symptom management [Internet]. [cited 2025 Nov]. Available from: https://www.sciencedirect.com/topics/medicine-and-dentistry/symptom-management
