4 results
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Condition characterized by progressive loss or damage of neurons.
Reference:
ScienceDirect Topics. Neurodegenerative disorder [Internet]. [cited 2025 Nov]. Available from: https://www.sciencedirect.com/topics/neuroscience/neurodegenerative-disorder
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Clumps of abnormal tau inside neurons that disrupt their function and lead to cell death.
Reference:
Samudra N, Lane-Donovan C, VandeVrede L, Boxer AL. Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues. J Clin Invest. 2023;133(12):e168553. doi:10.1172/JCI168553
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Structural proteins of neurons; their breakdown products in blood or CSF reflect non-specific axonal damage and neurodegeneration.
Reference:
Chouliaras L, Thomas A, Malpetti M, et al. Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 2022;93(6):651-658. doi:10.1136/jnnp-2021-327788
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Chronic inflammatory response of the central nervous system to damage, often contributing to neurodegeneration and disease progression.
Reference:
ScienceDirect Topics. Neuroinflammation [Internet]. [cited 2025 Nov]. Available from: https://www.sciencedirect.com/topics/medicine-and-dentistry/neuroinflammation
